Applications

Concussion

Concussion

Diagnostic Tool

Diagnostic Tool

Arthritis

Arthritis

Psoriasis

Psoriasis

Water Sanitation

Water Sanitation

Cancer

Cancer

Drug Delivery

Drug Delivery

 Concussion (Cereprol)

 

 

Concussions are a form of traumatic brain injury caused by a physical blow and typically result in immediate and noticeable mental impairment that fades quickly. They may result in long term structural changes that are not obvious in the immediate aftermath of the concussion (1). Interest in concussions has risen greatly in recent years due to the attention being paid to the injury in the National Football League (NFL). The NFL paid out $765 million to former players who brought a class action lawsuit during the 2013-2014 season. During that season there were at least 152 cases of concussions. It’s clear that new diagnostic and treatment procedures must be developed to reduce the chances of long term mental impairment from traumatic brain injuries (2).

 

 
According to the NIH, damage to the two protective coats of the brain is a significant contributing factor to brain tissue damage immediately after mild brain trauma or a concussion. The two protective coats are the Glia limitans, being the inner coat closest to the brain, and the meninges, the outer coat closest to the inner skull. When these coats are damaged, molecules from outside the skull diffuse all the way into the brain causing chemical damage in addition to physical damage. It was found that gluthathione, an antioxidant 17 times as massive as water was able to diffuse from the surface of the skull into the brain.
Gluthathione is able to decrease the levels of reactive oxygen species in the brain after trauma. In an experiment conducted on mice it was shown that application of gluthathione to the skull after brain injury reduced the rate of neural cell death by 67%. Our technology can provide better and quicker results than glutathione, and in a non-invasive fashion. We have direct control over voltage and amperage of the free electrons, pure antioxidants. Molecules like glutathione work by donating an electron to a reactive oxygen species. We cut out the need for a middle man molecule and donate the electrons in much larger and more controllable quantities to neutralize the reactive oxygen species. Since electrons are 10 orders of magnitude smaller than glutathione they will diffuse to the brain quicker even though there are extra barriers, skin and hair, in place.

1. P. McCory. “Consensus statement on Concussion in Sport–the 3rd International Conference onConcussion in Sport held in Zurich.” SAJSM. 2009; 21(2): 36- 46 http://www.ajol.info/index.php/sasma/article/download/44484/27996 2014 August 13
2. JM Breslow. “NFL Concussions: The 2013-2014 Season in Review”. Frontline. 2014; http://www.pbs.org/wgbh/pages/frontline/sports/concussion-watch/nfl-concussions-the-2013-14-season-in-review/ 2014 August 13
3. National Institue of Health, National Institute of Neurological Disorders and Stroke. “Concussion secrets unveiled in mice and people” [Press release]. 2013 http://www.ninds.nih.gov/news_and_events/news_articles/pressrelease_concussion_secrets_12082013.htm 2014 May 7